Irene Tupuna (born 18 September 1959), also known as Matangaro Tupuna, is an international lawn bowler from the Cook Islands.
Tupuna won the bronze medal in the triples at the 2007 Asia Pacific Bowls Championships in Christchurch.
She has been selected to represent the Cook Islands at two Commonwealth Games; the singles at the 2010 Commonwealth Games and the triples and fours at the 2014 Commonwealth Games.