Iran competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021. This was their ninth consecutive appearance at the Summer Paralympics since 1988.
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Iran qualified one athlete in Men's Individual W1, one athlete in Men's Individual Compound Open, two ticket in Men's Individual Recurve, one athlete in Women's Individual Compound and one athlete in Women's Individual Recurve.
16 athletes in 19 events represented Iran at the 2020 Summer Paralympics.
Iran sent one cyclist after successfully getting a slot in the 2018 UCI Nations Ranking Allocation quota for Asia.
Iran has qualified two athletes in Men's events in 90 and +100 kg.
Iran has qualified one athlete in Women's KL3 events and one athlete in Men's VL2.
Iran entered five athletes into the Paralympic competition. All of them successfully broke the Paralympic qualification at the 2018 WSPS World Championships which was held in Cheongju, South Korea, 2019 WSPS World Cup which was held in Al Ain, United Arab Emirates and 2019 WSPS World Championships which was held in Sydney, Australia.
Iran's men's sitting volleyball team qualified for the 2020 Summer Paralympics after winning the 2018 World ParaVolley Championships.
Iran qualified three athletes to compete at the Paralympics competition. Two of them qualified by entered top six in the world ranking, while the other athlete qualified by winning the gold medal at the 2021 Asian Qualification Tournament in Amman, Jordan.
Iran's men's wheelchair basketball team qualified for the 2020 Summer Paralympics after finishing in top three at the 2019 IWBF Asia Oceania Wheelchair Basketball Championship in Pattaya, Thailand.