The Institute of Mathematical Sciences (IMSc) (sometimes also referred to as Matscience) is a research centre located in Chennai, India. It is a constituent institute of the Homi Bhabha National Institute.
IMSc is a national institute for fundamental research in frontier disciplines of the mathematical and physical sciences: theoretical computer science, mathematics, theoretical physics, and computational biology. It is funded mainly by the Department of Atomic Energy. The institute operates the Kabru supercomputer.
The institute was founded by Alladi Ramakrishnan in 1962 in Chennai. It is modelled after the Institute for Advanced Study, Princeton, New Jersey, United States. It went through a phase of expansion when E. C. G. Sudarshan in the 1980s and R. Ramachandran in 1990s were the directors. Amritanshu Prasad is currently the director of the institute.
The institute has a graduate research program to which a group of students are admitted each year to work towards a Ph.D. degree. IMSc hosts scientists at the post-doctoral level and supports a visiting scientist program in areas of research in the institute.
Located in South Chennai, in the Adyar-Tharamani area, the institute is on the Central Institutes of Technology (CIT) campus. The institute maintains a student hostel, flatlets for long-term visitors, married students and post-doctoral fellows, and the institute guest house. IMSc has its own faculty housing in Thiruvanmiyur near the seashore.