was born in Hino, Tokyo. He was the captain of the sixth unit of the Shinsengumi which were a special police force for the Tokugawa regime. Inoue was the oldest unit captain of the Shinsengumi.
Like his older brother, Inoue Matsugoro, Inoue Genzaburà  was also a practitioner of the Tennen Rishin-ryà « and mastered all the techniques of the school in 1860. However, it is a misconception that he lived at the Shieikan. In 1863, he joined the Rà Âshigumi together with Kondà  Isami and other members of the Shieikan.
Inoue Genzaburà  was related to Okita Rintarà  (Okita Sà Âji's brother-in-law).
He arrested eight members of the Ishin Shishi during the Ikedaya Affair in 1864.
Inoue died during the Battle of TobaâÂÂFushimi (the first battle of the Boshin War) in January 1868.
Inoue is featured in Kaze Hikaru (manga), Getsumei Seiki (manga), Studio Deen's Hakuà Âki: Shinsengumi Kitan (anime), and The Blue Wolves of Mibu (manga and anime.) He is also depicted in the 1999 film Gohatto and NHK's drama series Shinsengumi!, as well as in the Sega video game ' and its remastered edition ', where he is the equivalent of Osamu Kashiwagi.