Indole-3-acetaldehyde reductase (NADH)

In enzymology, indole-3-acetaldehyde reductase (NADH) () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are tryptophol and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its products are indole-3-acetaldehyde, reduced NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (indol-3-yl)ethanol:NAD⁺ oxidoreductase. Other names in common use include indoleacetaldehyde reductase, indole-3-acetaldehyde reductase (NADH), and indole-3-ethanol:NAD⁺ oxidoreductase. This enzyme participates in tryptophan metabolism.

See also

• Indole-3-acetaldehyde reductase (NADPH) which catalyses the same reaction with the cofactor nicotinamide adenine dinucleotide phosphate

References