The IWA World Championship is the major title in the IWA Mid-South based in Louisville, Kentucky. The title debuted at the "Crowning of a Champion" event on April 3, 1997, when Tower of Doom won a twelve-man tournament. There have been a total of 125 reigns among 59 champions and 19 vacancies. Tower of Doom was the inaugural champion, having defeated Ox Harley and Bull Pain in a tournament final three-way match on April 4, 1997, at Crowning of Champion. On June 14, 2022, Jake Crist vacated the title after failing to receive payment. As a result, the company ceased operations and the title was deactivated.
As of , .