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Centpyraquin

Centpyraquin, also known as IHCH-7162 or as compound 69-183, is a serotonin receptor modulator related to the partial ergolines and phenylpiperazines. It is a serotonin 5-HT<sub>1A</sub> receptor agonist and a mixed modulator of the serotonin 5-HT<sub>2A</sub> receptor, acting as a weak partial agonist of G protein signaling and as an antagonist of β-arrestin2 recruitment. The drug has antipsychotic-like, CNS depressant, and antihypertensive effects in animals. Centpyraquin was developed by researchers in India and first described by the 1970s before being studied and described further in 2024.

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