Hypoxia preconditioned plasma or hypoxia pre-conditioned plasma (abbreviated as HPP) is the (cell-free) plasma obtained after extracorporeal conditioning (i.e. culturing) of anticoagulated blood under physiological temperature (37 ðC) and physiological hypoxia (1âÂÂ5 %O<sub>2</sub>). Blood conditioning is typically carried out over 2 to 4 days.
No high quality evidence supports its use for any medical purpose as of 2016.