Hoseynabad Rural District () is in Mehrdasht District of Najafabad County, Isfahan province, Iran. Its capital is the village of Hoseynabad.
At the time of the 2006 National Census, the rural district's population was 5,440 in 1,372 households. There were 5,220 inhabitants in 1,529 households at the following census of 2011. The 2016 census measured the population of the rural district as 4,687 in 1,444 households. The most populous of its 29 villages was Hoseynabad, with 3,087 people.