The Honda CBR250RR is a CBR series ' twin-cylinder sport bike made by Astra Honda Motor, a subsidiary of Honda in Indonesia. It was unveiled in July 2016 in Jakarta. Production was started in November of the same year for the 2017 model year. It is the first CBR motorcycle to have a twin-cylinder engine on RR moniker. It is also the smallest Honda motorcycle to wear a CBR-RR badge. Previously, Honda also used the CBR250RR name for their four-cylinder sport bike sold between 1990 and 1996. The bike is officially sold in Indonesia, Japan, Hong Kong, Macau, Thailand, and Malaysia.
According to Honda, the CBR250RR has technologies derived from the RC213V MotoGP bike, including throttle-by-wire technology, three riding modes, and a more compact engine design than its competitors.
The basis for the CBR250RR was Honda's Light Weight Super Sports Concept that was shown at the 2015 Tokyo Motor Show. The concept bike had a parallel-twin engine that redlined at 14,000 rpm.
The CBR250RR received its first update in July 2020, which included assist and slipper clutch as standard equipment. The compression ratio was increased by changing the piston shape, using a smaller diameter balancer. This and other updates increases the power and torque figures to and . The quickshifter became available as an option, except for Indonesian SP model where it became standard.
The CBR250RR received its second update in September 2022.
, the CBR250RR has participated in Asia Road Racing Championship at Asia Production 250cc (AP250) class. The bike produces more than and weighs . It won the championship in its debut season as well as the following year. The CBR250RR has also been raced in the Indonesian Indospeed Race Series championship and Malaysia Superbike Championship.
Some performance tests listed here were conducted by Otomotif tabloid from Indonesia in December 2016.