Holy Rosary Church Complex is a historic Roman Catholic church complex located in the Edgerton neighborhood of Rochester, Monroe County, New York. The complex consists of the church (1916), rectory (c. 1916), convent (1911), and two-story garage. All buildings in the complex are in a Spanish eclectic, Arts and Crafts style. The buildings are constructed of hollow tile brick and three feature their original Spanish clay tile roofs. The church features a rose window in the Mudéjar style similar to that of the Mission San Carlos Borromeo de Carmelo. The church also features a square brick bell tower in the southwest corner.
The complex was listed on the National Register of Historic Places in 2012.