Holy Blood is an alternative term for the Blood of Christ and may refer to:
- Relic of the Holy Blood, any of several relics claiming to be the blood of Christ
- Basilica of the Holy Blood, a church in Bruges
- Heiligenblut am GroÃÂglockner, a municipality in Austria
- Holy Blood (band), a Ukrainian Christian black / folk metal band
- Holy Blood of Wilsnack, a pilgrim site in Germany
- Procession of the Holy Blood, a procession in Bruges
- Santa Sangre, a film by Alejandro Jodorowsky
- The Holy Blood and the Holy Grail, a book by Michael Baigent, Richard Leigh, and Henry Lincoln
See also