Holme railway station is a former station in Holme, Cambridgeshire.
The first section of the Great Northern Railway (GNR) - that from to a junction with the Manchester, Sheffield and Lincolnshire Railway at Grimsby - opened on 1 March 1848, but the southern section of the main line, between and , was not opened until August 1850. Holme was one of the original stations, opening with the line on 7 August 1850.
On 1 August 1863 Holme became a junction station with the opening of the Ramsey Railway, between Holme and Ramsey.
The Ramsey branch closed to passengers on 6 October 1947, and Holme station closed on 6 April 1959.