The tenth cycle of Holland's Next Top Model premiered on 4 September 2017 on RTL 5. Anouk Smulders was replaced by cycle 9 judge Anna Nooshin as the show's new host. Judges Alek Bruessing and Fred van Leer did not return for the new cycle. The new panel of judges was composed of cycle 2 winner Kim Feenstra, photographer Nigel Barker and stylist JeanPaul Paula.
The prizes for this cycle included a modelling contract with VDM Model Management, a fashion spread in Elle magazine, and a campaign for HEMA.
The winner of the competition was 19 year-old Montell van Leijen from Deventer.
This cycle introduced the participation of male contestants. Application was restricted exclusively to female contestants in prior cycles of the show. The show also saw the return of linear call-outs at elimination. The last cycle to follow the format was cycle 5 in 2011.
(Ages stated are at start of contest)