Hisham Layous (, ; born 13 November 2000) is an Israeli professional footballer who plays as a forward for Greek Super League club Levadiakos, on loan from Maccabi Tel Aviv.
Layous was born in Mi'ilya, Israel, to an Arab-Christian family.
Layous is a product of the different Israeli football youth sportive systems.
He signed contract with a Ukrainian side Karpaty Lviv in July 2019 and made his debut for FC Karpaty as a second half-time substituted player in a home losing game against FC Dynamo Kyiv on 31 July 2019 in the Ukrainian Premier League.