His Brother's Wife is a 1916 silent American drama film directed by Harley Knoles and starring Carlyle Blackwell and Ethel Clayton. It was produced by Premo Feature Film Corporation and distributed by the World Film Company.
Motography reviewer Hugh Hoffman gave the film a positive review, saying of the cinematography "The photographer's name is not given, but it should be, because his work is very fine."
The New York Clipper's review was negative, describing the film as being "a tiresome bit of mechanical and ultra conventional melodramatic nonsense."
Lynde Denig's review for Moving Picture World was positive, finding the story to be "adequate" and the actors as having done "their share."
A complete copy of the film survives in the Library of Congress collection.