Hinojosa de Duero is a village and large municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile-Leon. It is located from the provincial capital city of Salamanca and has a population of 699 people.
The municipality covers an area of . It lies above sea level.
The basis of the economy is agriculture. The village is also known for its local cheese ("queso de Hinojosa"), which is an aged cheese made with sheep milk, similar to Manchego.
The city celebrates the San Juan festival on 24 June.