Highland is an unincorporated community in Cinque Hommes Township in Perry County, Missouri, United States.
Highland's name is topographical and was named after a nearby creek. It is located in the north-central part of Cinque Hommes Township. A post office was maintained there between 1891 â 1904.
The community has a Catholic church, St. Joseph parish, which was founded in 1870.
Highland is located four and one-half miles southwest of Perryville.