Henry Fork is an unincorporated community and census-designated place (CDP) in Franklin County, Virginia, United States, just south of Rocky Mount. As of the 2020 census, Henry Fork had a population of 1,120.
The community is in central Franklin County, centered at the junction of the U.S. Route 220 Rocky Mount bypass with U.S. Route 220 Business (South Main Street), south of the center of Rocky Mount. US 220 leads north to Roanoke and south to Martinsville.
According to the U.S. Census Bureau, the Henry Fork CDP has a total area of , of which , or 0.34%, is water. The Pigg River, an east-flowing tributary of the Roanoke River, forms the northern edge of the CDP and its border with Rocky Mount.
Henry Fork was first listed as a census designated place in the 2010 U.S. census.