Henry Erskine may refer to:
- Henry Erskine, Master of Cardross (died 1628), Scottish landowner
- Henry Erskine (minister) (1624âÂÂ1696), Scottish Presbyterian minister
- Henry Erskine, 3rd Lord Cardross (1650âÂÂ1693), covenanter
- Sir Henry Erskine, 5th Baronet (c. 1710âÂÂ1765), member of parliament for Ayr Burghs, 1749âÂÂ1754, and for Anstruther Easter Burghs, 1754âÂÂ1765
- Henry Erskine, 10th Earl of Buchan (1710âÂÂ1767), Scottish peer
- Henry Erskine (lawyer) (1746âÂÂ1817), MP for Haddington Burghs, 1806, and for Dumfries Burgh, 1806âÂÂ1807
- Henry Erskine, 12th Earl of Buchan (1783âÂÂ1857)
- Henry Erskine (priest) (died 1859), second son of Lord Erskine and Anglican dean of Ripon Minster
- Henry Napier Bruce Erskine (1831âÂÂ1893), member of the Indian Civil Service
- Sir (Henry) David Erskine of Cardross (1838âÂÂ1921), Scottish military officer and Serjeant-at-Arms of the House of Commons
- Henry Thomas Alexander Erskine, 18th Earl of Buchan (born 1960), Scottish peer and landowner