Henderson is an unincorporated community and census-designated place (CDP) in Baxter County, Arkansas, United States. It was first listed as a CDP in the 2020 census with a population of 309. Henderson is located on the east bank of Norfork Lake along U.S. Routes 62 and 412, east-northeast of Mountain Home. Henderson has a post office with ZIP code 72544.
Almost all of the CDP is in the Mountain Home School District. A small piece is in the Viola School District.