Hemidactylus makolowodei is a species of African gecko, a lizard in the family Gekkonidae.
The specific name, makolowodei, is in honor of Central African herpetologist .
As of 2018, Hemidactylus makolowodei is endemic to Cameroon, although its range is likely to extend into Nigeria.
The preferred habitats of Hemidactylus makolowodei are forest and savanna, at altitudes of .
Hemidactylus makolowodei is a large gecko, with a snout-to-vent length (SVL) of . Dorsally, it is purplish. The male has 45 precloacal-femoral pores.
Hemidactylus makolowodei preys upon arthropods.
Hemidactylus makolowodei is oviparous.