Doxercalciferol (or 1-hydroxyergocalciferol, trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease. It is a synthetic analog of ergocalciferol (vitamin D<sub>2</sub>). It suppresses parathyroid synthesis and secretion.
Doxercalciferol is the vitamin D<sub>2</sub> analogue of alfacalcidol. It undergoes 25-hydroxylation in the liver to become the active ercalcitriol, without the involvement of kidneys.