Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C<sub>21</sub>H<sub>27</sub>NO<sub>5</sub>. The enantiomer of the natural product is being studied as a potential painkiller. Hasubanonine is structurally related to the morphinan class of opioid analgesics.
The enantioselective total synthesis of (âÂÂ)-hasubanonine and related natural products, (âÂÂ)-runanine, (âÂÂ)-delavayine, and (+)-periglaucine B were first achieved by Prof. Seth Herzon and co-workers at Yale University in 2011.