Handley is a surname. Notable people with the surname include:
- Brian Handley, soccer player
- Benjamin Handley (1784âÂÂ1858), English politician and member of parliament for Boston
- Carol Handley, Classics educator
- Chris S. Handley, comic collector in United States v. Handley
- David Handley (farmer), activist
- Dick Handley (1922âÂÂ2012), American football player
- Elizabeth Handley-Seymour (c. 1873âÂÂ1948), English fashion designer
- Eric Handley CBE (1926âÂÂ2013), professor of Greek at Cambridge and University College, London
- George Handley (disambiguation), multiple people, including
* George Handley (politician) (1752âÂÂ1793), American politician, Governor of Georgia, 1788âÂÂ1789:
* George Handley (footballer, born 1868) (1868âÂÂ1938), English footballer
* George Handley (footballer, born 1886) (1886âÂÂ1952), English footballer
* George Handley (footballer, born 1912) (1912âÂÂ1943), English footballer
* George B. Handley, professor of humanities at Brigham Young University
- Harold W. Handley, Indiana governor
- Jody Handley, English footballer
- Joe Handley, premier of Northwest Territories, Canada
- Lee Handley (1913âÂÂ1970), Major League baseball player
- Matthew Handley, radio host on Ave Maria Radio
- Paul M. Handley, American journalist, wrote The King Never Smiles (biography of Thai King Bhumibol)
- Ray Handley, American football coach
- Taylor Handley, actor
- Tommy Handley, comedian
- Vernon Handley, conductor
- Wayne Handley, airshow performer
- Wal Handley, motorcycle racer