Handball competitions at the 2023 Pan American Games were held from 24 October to 4 November 2023. The venue for the competition was the Gimnasio Polideportivo located in Viña del Mar.
A total of eight men's and eight women's teams (each consisting up to 14 athletes) competed in each tournament. This means a total of 224 athletes competed at the games.
The winner of each competition qualified for the 2024 Summer Olympics in Paris, France.
Eight men's teams and eight women's teams qualified to compete at the games in each tournament. Chile, as the host nation, received automatic qualification in both tournaments, along with seven other teams.