Han Zaifen (; born 20 March 1968) is a Chinese performer of Huangmei opera who is widely regarded as a Huangmei opera superstar. She is the only Huangmei opera artist to have won the prestigious Plum Blossom Award twice. She performed on CCTV Spring Festival Gala a total of seven times. She also starred in some non-musical TV series.
Han was born in Qianshan, Anqing, Anhui province in 1968.