Kassem Hamzé (; born 2 January 1950) is a Lebanese former footballer and sprinter.
As a football player, he played for the Lebanon national football team, scoring during the qualification tournament for the 1972 Summer Olympics in November 1971. As a sprinter, he competed in the men's 400 metres and men's 800 metres at the 1972 Summer Olympics, where he was eliminated in the first round.