HOT-7, also known as 4-propylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-7, is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-7. The drug is taken orally.
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists HOT-7's dose range as 15 to 20mg orally and its duration as 6 to 8hours. The drug's onset and peak of effects were not described. HOT-7's properties are similar to those of 2C-T-7, which has a dose of 10 to 30mg orally and a duration of 8 to 15hours, although HOT-7 may have a somewhat shorter duration. HOT-7 may act as a prodrug of 2C-T-7.
The effects of HOT-7 have been reported to include being "quite psychedelic", very rich in closed-eye imagery, not as much in terms of open-eye visuals, very good for interpretive and conceptual thinking, emotional changes, feeling "smoothly stoned", lightheadedness, alcohol-like tipsiness and wooziness, social avoidance, and gastrointestinal disturbances.
The chemical synthesis of HOT-7 has been described.
Analogues of HOT-7 include 2C-T-7, HOT-2 (N-hydroxy-2C-T-2), and HOT-17 (N-hydroxy-2C-T-17), among others.
HOT-7 was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).
HOT-7 is a controlled substance in Canada under phenethylamine blanket-ban language.
This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.