HMS Artemis (P449) was an of the Royal Navy, built by Scotts Shipbuilding & Engineering Co. of Greenock and launched 28 August 1946. The submarine sank while refueling in 1971, was raised and sold for breaking up in 1972.
Like all Amphion-class submarines, Artemis had a displacement of when at the surface and while submerged. She had a total length of , a beam of , and a draught of . The submarine was powered by two Admiralty ML eight-cylinder diesel engines generating a power of each. She also contained four electric motors each producing that drove two shafts. She could carry a maximum of of diesel, although she usually carried between .
The submarine had a maximum surface speed of and a submerged speed of . When submerged, she could operate at for or at for . When surfaced, she was able to travel at or at . She was fitted with ten torpedo tubes, one QF 4 inch naval gun Mk XXIII, one Oerlikon 20 mm cannon, and a .303 British Vickers machine gun. Her torpedo tubes were fitted to the bow and stern, and she could carry twenty torpedoes. Her complement was sixty-one crew members.
In September 1952 Artemis deployed to Canada a second time for anti-submarine training with the Royal Canadian Navy. Artemis replaced the damaged , which had developed issues while training with vessels of the Royal Canadian Navy off Bermuda. In 1953 she took part in the Fleet Review to celebrate the Coronation of Queen Elizabeth II.
On 1 July 1971 Artemis sank in of water while moored at the shore establishment HMS Dolphin at Gosport during refuelling. The sub dipped by the stern (she was being prepared for fuelling using the aft externals) which filled and the sub sank. All aboard escaped, with decisive action by four crew members resulting in bravery awards. She was raised on 6 July and decommissioned, sold to be broken up for scrap on 12 December 1971.