Gvardeysky District () is an administrative district (raion), one of the fifteen in Kaliningrad Oblast, Russia. It is located in the center of the oblast. The area of the district is . Its administrative center is the town of Gvardeysk. Population: 32,101 (2002 Census); The population of Gvardeysk accounts for 46.4% of the district's total population.
The district is situated in the center of the oblast, east of Kaliningrad, the administrative center of the oblast.
Main rivers in the district include the Pregolya and its branch the Deyma.
Within the framework of administrative divisions, Gvardeysky District is one of the fifteen in the oblast. The town of Gvardeysk serves as its administrative center.
As a municipal division, the district has been incorporated as Gvardeysky Urban Okrug since June 11, 2014. Prior to that date, the district was incorporated as Gvardeysky Municipal District, which was subdivided into one urban settlement and four rural settlements.
The district is among the more densely populated districts of the oblast.
District economy is agrarian. The main railway line and road from Kaliningrad to Moscow pass through the district, parallel with the Pregolya.