Gulou District () is a district of the city of Xuzhou, Jiangsu province, China. It is named after the drum tower of Xuzhou, which built in 1379 but ruined in 1952 because of falling into disrepair. Gulou District was a traditional business district before its expansion.
In 1938, the urban area of Tongshan County, namely the former No. 1 District was separated out to establish Xuzhou City by the occupying Imperial Japanese military. KMT retained this administrative division after capitulation of Japan. It was renamed Gulou in 1955. After the Cultural Revolution began, it was renamed Yan'an (named after former communist revolutionary headquarter, Yan'an) in 1967, thereafter was restored its former name in 1980. Xuzhou Economic and Technological Development Zone was transferred to Gulou from Tongshan in 2005.
In the present, Gulou District has 8 subdistricts and 1 towns.