Guazapares is one of the 67 municipalities of Chihuahua, in northern Mexico. The municipal seat lies at Témoris. The municipality covers an area of 2,145.8 km<sup>2</sup>.
As of 2010, the municipality had a total population of 8,998, up from 8,010 as of 2005.
The municipality had 492 localities, the largest of which (with 2010 populations in parentheses) was: Témoris (2,053), classified as rural.
As a pueblo, Guazapares was home to the Guazapare people, a tribal group who spoke a dialect of the Tarahumara language. After Jesuit missionaries Julio Pascual and Manuel Martinez were killed in a 1632 uprising, led a punitive expedition against native groups including the Guazapare, killing about 800 natives. The surviving Guazapare were reduced into the Jesuit missions.
The municipality has 352 localities. The largest are: