Grigore Gheorghe Cantacuzino (1872 – 1930) was a Romanian Conservative politician who served as Mayor of Bucharest from March to December 1913. The son of Gheorghe Grigore Cantacuzino and brother of Mihail G. Cantacuzino, he married Alexandrina Pallady.
One of his sons, Alexandru Cantacuzino, became a prominent figure in Romania's fascist Legionary Movement.