Greek National Road 22 (), abbreviated as EO22, is a major national road in northwestern Greece. The EO22 runs within the Ioannina regional unit, from Kalpaki to the border crossing with Albania near Kakavijë, and is part of European route E853.
The EO22 is officially defined as an eastâÂÂwest road within the Ioannina regional unit, branching off the EO20 at Kalpaki, and heading west to the border crossing with Albania, near Kakavijë. The entire road is part of European route E853, which runs from the AlbanianâÂÂGreek border to Ioannina, the capital of both the regional unit and Epirus.
On 15 December 1995, the EO22 became part of the basic (primary) national road network.
Ministerial Decision G25871 of 9 July 1963 created the EO22 from the old EO29, which existed by royal decree from 1955 until 1963, and followed the same route as the current EO22.
From 1950 to 1962, the road was part of the old E19. The EO22 became part of the International E-road network on 15 March 1983, originally as part of the E851 until 12 September 1986, and then as part of the E853 thereafter.
If the A5 motorway is extended from Pedini to Kakavia, the E853 will be rerouted away from the EO22.