Great Slave is a territorial electoral district for the Legislative Assembly of the Northwest Territories, Canada. It is one of seven districts that represent Yellowknife.
The district has existed twice, the first incarnation (under the district name of Great Slave Lake) existed from 1975 and was abolished in 1979 when it was split between Great Slave East and Rae-Lac La Martre. The second incarnation was created in 1999 from the old Yellowknife North riding.