In the geometry of hyperbolic 4-space, the great 120-cell honeycomb is one of four regular star-honeycombs. With Schläfli symbol {5,5/2,5,3}, it has three great 120-cells around each face. It is dual to the order-5 icosahedral 120-cell honeycomb.
It can be seen as a greatening of the 120-cell honeycomb, and is thus analogous to the three-dimensional great dodecahedron {5,5/2} and four-dimensional great 120-cell {5,5/2,5}. It has density 10.