Gmina Wielkie Oczy is a rural gmina (administrative district) in Lubaczów County, Subcarpathian Voivodeship, in south-eastern Poland, on the border with Ukraine. Its seat is the village of Wielkie Oczy, which lies approximately south of Lubaczów and east of the regional capital Rzeszów.
The gmina covers an area of , and as of 2006 its total population is 3,929 (3,904 in 2013).
Gmina Wielkie Oczy contains the villages and settlements of Bihale, Czopy, Dumy, Gieregi, Kobylnica Ruska, Kobylnica Woà Âoska, à Âukawiec, Majdan Lipowiecki, Mielnik, Niwa, Podà Âozy, Potok Jaworowski, Skolin, Sople, Szczeble, Tarnawskie, Wielkie Oczy, Wola, Wólka à »mijowska, Zagrobla and à »mijowiska.
Gmina Wielkie Oczy is bordered by the gminas of Laszki and Radymno. It also borders Ukraine.