In molecular biology, Glycoside hydrolase family 12 is a family of glycoside hydrolases.
Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.
Glycoside hydrolase family 12 CAZY GH_12 comprises enzymes with the following activities: endoglucanase (), xyloglucan hydrolase (), ò-1,3-1,4-glucanase () and xyloglucan endotransglycosylase (). These enzymes were formerly known as cellulase family H.