Glenns Run is a long 2nd order tributary to the Ohio River in Ohio County, West Virginia.
According to the Geographic Names Information System, it has also been known historically as:
Glenns Run rises about 2 miles east of Wheeling, West Virginia, and then flows westerly to join the Ohio River in the Warwood neighborhood of Wheeling, West Virginia.
Glenns Run drains of area, receives about 40.2 in/year of precipitation, has a wetness index of 304.81, and is about 70% forested. It also is orange in color presumably from mine drainage which can be seen from Google satellite images.