Gishu Mindaye (born August 18, 1986) is an Ethiopian long distance track, and road running athlete.
Gishu won the 2006 Rotterdam Marathon on April 9 beating Helena Javornik and Isabel Elizmendi after 2:28:30, breaking away from Javornik passing the 35 km mark. In September that year she returned to Rotterdam taking part in the 1/2 Marathon. Gishu finished second behind Mara Yamauchi finishing almost two minutes earlier.