Girolamo Piccolomini, seniore was a Roman Catholic prelate who served as Bishop of Pienza (1498âÂÂ1510) and Bishop of Montalcino (1498âÂÂ1510).
On 14 March 1498, Girolamo Piccolomini was appointed during the papacy of Pope Alexander VI as both Bishop of Pienza and Bishop of Montalcino. He served as Bishop of Pienza and Bishop of Montalcino until his resignation in favor of his son of the same name, Girolamo Piccolomini (junior), on 9 Dec 1510.