Giovanni Castiglione de Polena (died 1 Sep 1456) was a Roman Catholic prelate who served as Bishop of Orvieto (1454âÂÂ1456) and Bishop of Penne e Atri (1433âÂÂ1454).
On 23 Mar 1433, Giovanni Castiglione was appointed by Pope Eugene IV as Bishop of Penne e Atri.
While bishop, he was the principal co-consecrator of Canute Mikkelsen, Bishop of Viborg (1452).
On 21 Oct 1454, he was appointed Bishop of Orvieto by Pope Nicholas V. He served as Bishop of Orvieto until his death on 1 Sep 1456.