Giovanni Battista Gentile Pignolo (Genoa, 1525 - Genoa, 1595) was the 71st Doge of the Republic of Genoa.
He was elected to the dogal title on 19 October 1577, the twenty-sixth in biennial succession and the seventy-first in republican history. After his office on 19 October 1579, Giovanni Battista Gentile Pignolo was appointed perpetual procurator and continued to serve the Genoese state for other years.