Gianni Del Buono (1 October 1943) is a former Italian middle distance runner.
He is the husband of the Italian middle-distance runner Rossella Gramola and the father of the middle-distance runner Federica Del Buono.
Gianni Del Buono won three medals, at senior level, at the International athletics competitions. He participated at two editions of the Summer Olympics (1968 and 1972), he has 31 caps in national team from 1963 to 1973.
Gianni Del Buono has won 7 times the individual national championship.