Gian Carlo Muzzarelli (born 22 June 1955 in Modena) is an Italian politician.
He is a member of the Democratic Party and he served as President of the Province of Modena from 2014 to 2018. He was elected Mayor of Modena on 8 June 2014 and took office on 10 June. He has been re-elected for a second term in 2019.