German submarine U-80 was a Type VIIC submarine of Nazi Germany's Kriegsmarine during World War II. She was laid down at the Bremer Vulkan Vegesacker Werft in Bremen as yard number 8 on 17 April 1940, launched on 11 February 1941 and commissioned on 8 April under Oberleutnant zur See Georg Staats.
U-80 spent her career as a training boat, first with the 1st U-boat Flotilla, then the 26th, 24th, 23rd and 21st flotillas. She sank or damaged no ships, but was herself sunk in a diving accident west of Pillau (now Baltiysk in modern Russia), on 28 November 1944.
German Type VIIC submarines were preceded by the shorter Type VIIB submarines. U-80 had a displacement of when at the surface and while submerged. She had a total length of , a pressure hull length of , a beam of , a height of , and a draught of . The submarine was powered by two MAN M6V 40/46 four-stroke, six-cylinder supercharged diesel engines producing a total of for use while surfaced, two Brown, Boveri & Cie GG UB 720/8 double-acting electric motors producing a total of for use while submerged. She had two shafts and two propellers. The boat was capable of operating at depths of up to .
The submarine had a maximum surface speed of and a maximum submerged speed of . When submerged, the boat could operate for at ; when surfaced, she could travel at . U-80 was fitted with two torpedo tubes at the bow, fourteen torpedoes, one SK C/35 naval gun, 220 rounds, and a C/30 anti-aircraft gun. The boat had a complement of between forty-four and sixty.