German submarine U-2546 was a Type XXI U-boat (one of the "Elektroboote") of Nazi Germany's Kriegsmarine, built for service in World War II. She was ordered on 6 November 1943, and was laid down on 22 November 1944 at the Blohm & Voss yard at Hamburg, as yard number 2546. She was launched on 19 February 1945, and commissioned under the command of Oberleutnant zur See Max Dobbert on 21 March 1945.
Like all Type XXI U-boats, U-2546 had a displacement of when at the surface and while submerged. She had a total length of (o/a), a beam of , and a draught of . The submarine was powered by two MAN SE supercharged six-cylinder M6V40/46KBB diesel engines each providing , two Siemens-Schuckert GU365/30 double-acting electric motors each providing , and two Siemens-Schuckert silent running GV232/28 electric motors each providing .
The submarine had a maximum surface speed of and a submerged speed of . When running on silent motors the boat could operate at a speed of . When submerged, the boat could operate at for ; when surfaced, she could travel at . U-2546 was fitted with six torpedo tubes in the bow and four C/30 anti-aircraft guns. She could carry twenty-three torpedoes or seventeen torpedoes and twelve mines. The complement was five officers and fifty-two men.
U-2546 was scuttled on 3 May 1945, at Kiel as part of Operation Regenbogen. The wreck was later raised and broken up.