German submarine U-169 was a Type IXC/40 U-boat of Nazi Germany's Kriegsmarine built for service during World War II. Her keel was laid down on 15 May 1941 by the Deutsche Schiff- und Maschinenbau AG in Bremen as yard number 708. She was launched on 6 June 1942 and commissioned on 16 November with Oberleutnant zur See Hermann Bauer in command.
German Type IXC/40 submarines were slightly larger than the original Type IXCs. U-169 had a displacement of when at the surface and while submerged. The U-boat had a total length of , a pressure hull length of , a beam of , a height of , and a draught of . The submarine was powered by two MAN M 9 V 40/46 supercharged four-stroke, nine-cylinder diesel engines producing a total of for use while surfaced, two Siemens-Schuckert 2 GU 345/34 double-acting electric motors producing a total of for use while submerged. She had two shafts and two propellers. The boat was capable of operating at depths of up to .
The submarine had a maximum surface speed of and a maximum submerged speed of . When submerged, the boat could operate for at ; when surfaced, she could travel at . U-169 was fitted with six torpedo tubes (four fitted at the bow and two at the stern), 22 torpedoes, one SK C/32 naval gun, 180 rounds, and a SK C/30 as well as a C/30 anti-aircraft gun. The boat had a complement of forty-eight.
The U-boat's service began with training as part of the 4th U-boat Flotilla. She then moved to the 10th flotilla on 1 March 1943 for operations.
She was sunk, in position , on 27 March 1943 by a British B-17 Flying Fortress of No. 206 Squadron RAF piloted by Flying Officer Ian Samuel.