George Nicholson may refer to:
- George Nicholson (diplomat) (floruit 1577âÂÂ1603), English agent in Scotland
- George Nicholson (printer) (1760âÂÂ1825), English printer
- George Nicholson (footballer) (1905âÂÂ?), English professional footballer
- George Nicholson (horticulturist) (1847âÂÂ1908), English horticulturist
- George Nicholson (rugby union) (1878âÂÂ1968), New Zealand rugby union player see The Original All Blacks
- George Nicholson (politician) (1868âÂÂ1935), Canadian Member of Parliament
- George Nicholson (sailor) (1937âÂÂ2025), British Olympic sailor
- George E. Nicholson Jr. (1918âÂÂ1971), American mathematician
- George M. Nicholson (1874âÂÂ1963), justice of the Oklahoma Supreme Court
- George Gibb Nicholson (1875âÂÂ1948), English-born Australian philologist and professor of French
- George Washington Nicholson (1832âÂÂ1912), American landscape painter